Alpha-arylethylpiperazine derivatives as neurokinin antagonists

The invention relates to new -arylethylpiperazine derivatives, which are useful as neurokinin receptor antagonists (NK 1 antagonists). It also relates to processes for the preparation of said -arylethylpiperazine derivatives, to their use for the prevention and/or treatment of a condition associated...

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Bibliographische Detailangaben
Hauptverfasser: Stiernet, Francoise, Genicot, Christophe, Lassoie, Marie-Agnes, Moureau, Florence, Ryckmans, Thomas, Taverne, Thierry, Henichart, Jean-Pierre, Neuwels, Michel, Goldstein, Solo
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to new -arylethylpiperazine derivatives, which are useful as neurokinin receptor antagonists (NK 1 antagonists). It also relates to processes for the preparation of said -arylethylpiperazine derivatives, to their use for the prevention and/or treatment of a condition associated with pathogical levels of substance P in a patient and to pharmaceutical compositions containing them.