Geometrically restricted 2-indolinone derivatives as modulators of protein kinase activity

The present invention relates to novel geometrically restricted 2-indolinones and physiologically acceptable salts thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cance...

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Bibliographische Detailangaben
Hauptverfasser: Miller, Todd Anthony, Tang, Peng Cho, Sun, Li, Tran, Ngoc My, Nematalla, Asaad, Nguyen, Anh Thi
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to novel geometrically restricted 2-indolinones and physiologically acceptable salts thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.