3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same
Disclosed are 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing such compounds. The 3,4,5-trisubstituted aryl nitrone compounds have formula (I); where R 1 -R 4 are as defined in the specification. The disclosed compositions are useful as therapeutics for inflamm...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | Disclosed are 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing such compounds. The 3,4,5-trisubstituted aryl nitrone compounds have formula (I); where R
1
-R
4
are as defined in the specification. The disclosed compositions are useful as therapeutics for inflammation-related conditions in mammals, such as arthritis, and as analytical reagents for detecting free radicals. |
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