DNA encoding bradykinin B1 receptor
DNAs encoding bradykinin B 1 receptors from mammalian cells have been cloned and characterized. The recombinant receptor is capable of forming receptors which bind des-Arg 10 kallidin and other B 1 -specific ligands. The DNA has been expressed in recombinant host cells which produce active recombina...
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| Sprache: | eng |
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| Zusammenfassung: | DNAs encoding bradykinin B
1
receptors from mammalian cells have been cloned and characterized. The recombinant receptor is capable of forming receptors which bind des-Arg
10
kallidin and other B
1
-specific ligands. The DNA has been expressed in recombinant host cells which produce active recombinant protein. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified. |
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