Contrast agents

The invention relates to ultrasound contrast agents comprising vesicles comprising a protein capable of formation of gas-containing vesicles, wherein the vesicles contain gas which comprises sulphur hexafluoride or a low molecular weight fluorinated hydrocarbon. These contrast agents exhibit stabili...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Klaveness, Jo, Rongved, Pal, Strande, Per
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to ultrasound contrast agents comprising vesicles comprising a protein capable of formation of gas-containing vesicles, wherein the vesicles contain gas which comprises sulphur hexafluoride or a low molecular weight fluorinated hydrocarbon. These contrast agents exhibit stability in vivo upon administration so as to permit ultrasound visualization while allowing rapid subsequent elimination from the system.