Extended release formulation of water-soluble drugs
A novel process for producing extended release formulation of a water-soluble drug comprising the steps of making a "modified drug" comprising a hot-melt granulation of the drug with soluble or dispersible polymeric material of a suitable molecular weight and melting point, coating portion...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | A novel process for producing extended release formulation of a water-soluble drug comprising the steps of making a "modified drug" comprising a hot-melt granulation of the drug with soluble or dispersible polymeric material of a suitable molecular weight and melting point, coating portions of the modified drug to different thicknesses or weights so as to produce subbatches, and blending the subbatches to achieve a specific drug release profile. |
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