Human NEDD-1

The invention provides isolated nucleic acids that encode human NEDD-1, and fragments thereof, vectors for propagating and expressing human NEDD-1 nucleic acids, host cells comprising the nucleic acids and vectors of the present invention, proteins, protein fragments, and protein fusions of human NE...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gu, Yizhong, Corrigan, Amy
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides isolated nucleic acids that encode human NEDD-1, and fragments thereof, vectors for propagating and expressing human NEDD-1 nucleic acids, host cells comprising the nucleic acids and vectors of the present invention, proteins, protein fragments, and protein fusions of human NEDD-1, and antibodies thereto. The invention further provides transgenic cells and non-human organisms comprising human NEDD-1 nucleic acids, and transgenic cells and non-human organisms with targeted disruption of the endogenous orthologue of the human NEDD-1 gene. The invention further provides pharmaceutical formulations of the nucleic acids, proteins, and antibodies of the present invention, and diagnostic, investigational, and therapeutic methods based on the human NEDD-1 nucleic acids, proteins, and antibodies of the present invention.