Compounds co-inducing cholinergic up-regulation and inflammation down-regulation and uses thereof

Compounds co-inducing cholinergic up-regulation and inflammation down-regulation and uses thereof

Chimeric compounds are disclosed which are covalent conjugates of reversible or irreversible cholinergic up-regulators and non-steroidal anti-inflammatory drugs (NSAIDs), methods for their synthesis and use thereof for treatment and/or prevention of central nervous system (CNS) disorders and disease...

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Bibliographische Detailangaben
Hauptverfasser: Amitai, Gabriel, Adani, Rachel, Rabinovitz, Ishai, Sod-Moriah, Gali, Meshulam, Haim
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Chimeric compounds are disclosed which are covalent conjugates of reversible or irreversible cholinergic up-regulators and non-steroidal anti-inflammatory drugs (NSAIDs), methods for their synthesis and use thereof for treatment and/or prevention of central nervous system (CNS) disorders and diseases.