Method of inducing or enhancing chondrogenesis with extracellular matrix containing BMP-4

A method and composition are provided for inducing or enhancing chondrogenesis in vivo or in vitro. The method is performed by exposing the cells in vitro or in vivo to an extracellular matrix comprising of type I collagen, type II collagen or a mixture of type I collagen or type II collagen and hya...

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Bibliographische Detailangaben
Hauptverfasser: Daverman, Robin, Heidaran, Mohammad
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A method and composition are provided for inducing or enhancing chondrogenesis in vivo or in vitro. The method is performed by exposing the cells in vitro or in vivo to an extracellular matrix comprising of type I collagen, type II collagen or a mixture of type I collagen or type II collagen and hyaluronate and further containing BMP-4 or a combination of BMP-4 and GDF-5.