PYRAZOLES AND PYRAZOLOPYRIMIDINES HAVING CRF ANTAGONISTIC ACTIVITY

The pyrazoles and pyrazolopyrimidines of the formula 1 wherein R 1 , R 2 , R 3 , R 4 and A are as defined herein, have corticotropin releasing factor (CRF) antagonist activity. As such, they are effective in the treatment of a wide range of diseases including stress-related illnesses.

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Bibliographische Detailangaben
Hauptverfasser: WELCH, WILLARD MCKOWAN, FARACI, WILLIAM STEPHEN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The pyrazoles and pyrazolopyrimidines of the formula 1 wherein R 1 , R 2 , R 3 , R 4 and A are as defined herein, have corticotropin releasing factor (CRF) antagonist activity. As such, they are effective in the treatment of a wide range of diseases including stress-related illnesses.