Process for the production of perbenzylated 1-0-glycosides

The invention relates to a process for the production of perbenzylated 1-O-glycosides of general formula I or salts thereof 1 in which sugar 1 is a monosaccharide that is functionalized in 1 -OH-position, R represents benzyl, n means 2, 3 or 4, means -O-, -S-, -COO- or -NH- and L means a straight-ch...

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Bibliographische Detailangaben
Hauptverfasser: Platzek, Johannes, Niedballa, Ulrich, Mareski, Peter
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a process for the production of perbenzylated 1-O-glycosides of general formula I or salts thereof 1 in which sugar 1 is a monosaccharide that is functionalized in 1 -OH-position, R represents benzyl, n means 2, 3 or 4, means -O-, -S-, -COO- or -NH- and L means a straight-chain, branched, saturated or unsaturated C 1 -C 30 carbon chain, which optionally is interrupted or substituted by groups. The process according to the invention starts from economical starting materials, provides good yields and allows the production of perbenzylated saccharides with 1-O-functionalized side chains on an enlarged scale.