Process for formulation of antibiotic compounds

The present invention involves a process for preparing a stable final formulation product of a compound of formula I, 1 or its pharmaceutically acceptable salt, hydrate or solvate by incorporating a suitable carbon dioxide source to an unstable monosodium adduct of carbapenem antibiotic compound.

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hunke, William, Illig, Kathleen, Kanike, Anand, Reynolds, Scott, Tsinontides, Stelios, Al-Dehneh, Anthony, Patel, Hiren
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention involves a process for preparing a stable final formulation product of a compound of formula I, 1 or its pharmaceutically acceptable salt, hydrate or solvate by incorporating a suitable carbon dioxide source to an unstable monosodium adduct of carbapenem antibiotic compound.