IMPROVED NUCLEIC ACIDS ENCODING A CHIMERIC GLYCOSYLTRANSFERASE

The invention relates to nucleic acids which encode glycosyltransferase and are useful in producing cells and organs from one species which may be used for transplantation into a recipient of another species. It also relates to the production of nucleic acids which, when present in cells of a transp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MCKENZIE, IAN FARQUHAR CAMPBELL, SANDRIN, MAURO SERGIO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to nucleic acids which encode glycosyltransferase and are useful in producing cells and organs from one species which may be used for transplantation into a recipient of another species. It also relates to the production of nucleic acids which, when present in cells of a transplanted organ, result in reduced levels of antibody recognition of the transplanted organ.