PEPTIDE DERIVATIVES

PEPTIDE DERIVATIVES

A peptide derivative having analgesic activity represented by the following Formula I: 1 wherein Q represents D-Arg or L-Arg; and X represents for example NR 6 -CHR 7 R 8 . Typical compounds include H 2 NC(NH)-Tyr-D-Arg-Phe-NHCH 2 CH 2 COOH and H 2 NC(NH)-Tyr-D-Arg-Phe-NHCH 2 CH 2 CONH 2 .

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Bibliographische Detailangaben
Hauptverfasser: SAKURADA, SHINOBU, MURAYAMA, KIMIE, NAKANO, MASAHARU, HONGO, KAZUYA, TAKESHIMA, SATOKO, TAKE, NOBUHIRO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A peptide derivative having analgesic activity represented by the following Formula I: 1 wherein Q represents D-Arg or L-Arg; and X represents for example NR 6 -CHR 7 R 8 . Typical compounds include H 2 NC(NH)-Tyr-D-Arg-Phe-NHCH 2 CH 2 COOH and H 2 NC(NH)-Tyr-D-Arg-Phe-NHCH 2 CH 2 CONH 2 .