POTENT AND BALANCED BIDIRECTIONAL PROMOTER

The invention provides a bidirectional hCMV-CAG4 promoter and recombinant vectors and recombinant virus comprising the bidirectional hCMV-CAG4 promoter operably linked to a first transgene in one direction and to a second transgene in the opposite direction. The invention also provides methods of ma...

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Bibliographische Detailangaben
1. Verfasser: Janseen Vacines & Prevention B.V
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides a bidirectional hCMV-CAG4 promoter and recombinant vectors and recombinant virus comprising the bidirectional hCMV-CAG4 promoter operably linked to a first transgene in one direction and to a second transgene in the opposite direction. The invention also provides methods of making and using such recombinant vectors and recombinant virus.