Method of Differentiating Oncogenic Changes of the Thyroid, A Kit to Embody the Method and the Use of Metallothionein (MT) for Differentiating Oncogenic Changes of the Thyroid

Method of Differentiating Oncogenic Changes of the Thyroid, A Kit to Embody the Method and the Use of Metallothionein (MT) for Differentiating Oncogenic Changes of the Thyroid

A method of differentiating oncogenic changes of the thyroid encompassing follicular adenoma and follicular cancer, characterised in that in a sample of oncogenic tissue from a patient the expression of the metallothionein (MT) potein is evaluated using immunochistochemical methods using monoclonal...

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1. Verfasser: Wroclawskie Centrum Badan EIT+Sp. z o.o
Format: Patent
Sprache:eng
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Zusammenfassung:A method of differentiating oncogenic changes of the thyroid encompassing follicular adenoma and follicular cancer, characterised in that in a sample of oncogenic tissue from a patient the expression of the metallothionein (MT) potein is evaluated using immunochistochemical methods using monoclonal anti-MT antibodies, the degree of intensity of the expression of metallothionein is evaluated under a light microscope using the semiquantitative IRS method according to Remmele, wherein if the degree of intensity of the expression of metallothionein is equal to or greater than 8 on the semiquantitative IRS scale then the presence of follicular cancer is indicated.