ACTIVE SUBSTANCE AND PHARMACEUTICAL COMPOSITION FOR TREATING ALCOHOL DEPENDENCE, AND A METHOD FOR OBTAINING AND THE USE OF SAID ACTIVE SUBSTANCE

1 14 14 2 14 3 4 14 5 17 14 The invention relates to novel drug substance for the treatment of alcohol dependence, pharmaceutical composition, medicament and method for treatment of dependence on using ethyl alcohol containing beverages.The invention provides a drug substance for treating alcohol dependence in human and warm-blooded animals representing substituted 1H-benzimidazoles of the general formula 1 or pharmaceutically acceptable salts and/or hydrates thereof wherein: W represents S or S═0 group; Rrepresents one or more substituent selected from hydrogen, halogen, C-Calkyl, C-Calkoxy, optionally substituted azaheterocyclyl; Rrepresents hydrogen or optionally substituted C-Calkyl; Rand Rindependently represent optionally identical substituents selected from hydrogen or optionally substituted C-Calkyl; Rrepresents an alkyl substituent selected from hydrogen, optionally substituted C-Calkyl, optionally substituted aryl, optionally substituted heterocyclyl, C-Calkoxycarbonyl, optionally substituted aminocarbonyl.