1D Periodic Corrugated Waveguides for Real-Time Detection of Increasing Concentrations of Thrombin

© 2020 Optical Society of America]. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modifications of the content of this paper are prohibited. [EN] An aptasensor based on periodic 1D corrugated waveguides is demonstrated to be suitable for the specific and continuous detection of thrombin at nM concentrations in real time with an estimated detection limit of 33.5 pM. This research was supported by a co-financed action by the European Union through the operational program of the European Regional Development Fund (FEDER) of the Valencian Community 2014-2020, the Generalitat Valenciana through the PROMETEO project AVANTI/2019/123 and the grant ACIF/2019/009, and by Universitat Politècnica de València through grants PAID-01-17 and the project OCUSENSOR. Martinez-Perez, P.; Gómez-Gómez, MI.; Torrijos-Morán, L.; Ivanova-Angelova, T.; Griol Barres, A.; Hurtado Montañés, J.; Bellieres, LC... (2020). 1D Periodic Corrugated Waveguides for Real-Time Detection of Increasing Concentrations of Thrombin. OSA (Optical Society). 1-2. https://doi.org/10.1364/iprsn.2020.ITu4A