Early experience and quality of life in SBRT prostate cancer boost of 9 Gy in a phase II trial

Purpose or ObjectiveExtracranial stereotactic body radiation therapy (SBRT) allows delivering high doses per fraction with high accuracy to the prostatic gland in a low number of fractions.Dose escalation in normofractionaded radiation prostate cancer trials showed an increased toxicity.In order to...

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Hauptverfasser: Ferrer, Ferran, Pont, Àngels, Blas, Rodolfo de, Boladeras, Anna, Garin, O, Ventura, Montse, Zardoya, Eva, Delgado, J, Condom, E, Merino, E, Mases, Joel, Castells-Esteve, Manel, Guix, Inés, Suarez, Jose Francisco, Gonzalez, Javier, Almendros, Sonia, Garcia, M, Berenguer, Miguel Ángel, Garcia, N, Stefanovic, M, Gutierrez, Cristina, Picon, Cristina, Ferrer, Montserrat, Guedea Edo, Ferran
Format: Tagungsbericht
Sprache:eng
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Zusammenfassung:Purpose or ObjectiveExtracranial stereotactic body radiation therapy (SBRT) allows delivering high doses per fraction with high accuracy to the prostatic gland in a low number of fractions.Dose escalation in normofractionaded radiation prostate cancer trials showed an increased toxicity.In order to evaluate the feasibility and toxicity of a regimen of a single dose hypofractionated prostate stereotactic boost a phase II study was undertaken. Self-reported quality of life (QOL) measures were also obtained in order to better define the possible deleterious effect of treatment.
ISSN:0167-8140
DOI:10.1016/S0167-8140(19)31959-0