Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients

Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients

Ivermectin has recently shown efficacy against SARS-CoV-2 in-vitro. We retrospectively reviewed severe COVID-19 patients receiving standard doses of ivermectin and we compared clinical and microbiological outcomes with a similar group of patients not receiving ivermectin. No differences were found b...

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Hauptverfasser: Camprubí, Daniel, Almuedo Riera, Alex, Martí Soler, Helena, Soriano Viladomiu, Alex, Hurtado, Juan Carlos, Subirà, Carme, Grau Pujol, Berta, Krolewiecki, Alejandro J, Muñoz Gutiérrez, José
Format: Artikel
Sprache:eng
Schlagworte:
COVID-19
Farmacologia
Pharmacology
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Zusammenfassung:Ivermectin has recently shown efficacy against SARS-CoV-2 in-vitro. We retrospectively reviewed severe COVID-19 patients receiving standard doses of ivermectin and we compared clinical and microbiological outcomes with a similar group of patients not receiving ivermectin. No differences were found between groups. We recommend the evaluation of high-doses of ivermectin in randomized trials against SARS-CoV-2.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0242184