Different alterations of glomerular filtration rate and their association with uric acid in children and adolescents with type 1 diabetes or with overweight/obesity

GFR alterations were different between youths with T1D and with OW/OB. Higher uric acid, older age, and puberty were related to lower GFR values in OW/OB children. Longitudinal studies will determine if low GFR is consequence of a rapid GFR decline in pediatric patients with OW/OB. Keywords: childre...

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Hauptverfasser: Santucci de Magistris, Maria, Muzzio, María L, Peredo, María S, Brovarone, Lucrecia, Scricciolo, Romina, Diez, Cecilia, Andrés Lacueva, Ma. Cristina, Kabakian, María L, Meroño, Tomás
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Sprache:eng
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Zusammenfassung:GFR alterations were different between youths with T1D and with OW/OB. Higher uric acid, older age, and puberty were related to lower GFR values in OW/OB children. Longitudinal studies will determine if low GFR is consequence of a rapid GFR decline in pediatric patients with OW/OB. Keywords: children; diabetes; hyperfiltration; obesity; renal disease; uric acid.
ISSN:1399-543X
DOI:10.1111/pedi.13008