Efficacy and safety of Pegylated Interferon-α2b Plus Ribavirin for the treatment of chronic hepatitis C in HIV-infected patients

Low response rates and concerns about safety have limited the implementation of treatment for chronic hepatitis C (CHC) in patients with HIV infection. The efficacy and safety of pegylated interferon (peg-IFN) plus ribavirin in HIV-infected patients with CHC were evaluated in a prospective, open-lab...

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Hauptverfasser:	Santín Cerezales, Miguel, Shaw Perujo, Evelyn, Garcia, Maria Jose, Delejido, Antonio, Rodríguez de Castro, Eduardo, Rota Roca, Rosa, Altés, Jordi, Baguena, Francisco, Valero, Silvia, Sala, Montserrat, Casanova Rituerto, Aurora, HCV/HIV-01 Study Team
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral agents Efecte dels medicaments sobre els microorganismes Effect of drugs on microorganisms Hepatitis C HIV infections Infeccions per VIH Interferon Interferó Medicaments antivírics
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Beschreibung
Zusammenfassung:	Low response rates and concerns about safety have limited the implementation of treatment for chronic hepatitis C (CHC) in patients with HIV infection. The efficacy and safety of pegylated interferon (peg-IFN) plus ribavirin in HIV-infected patients with CHC were evaluated in a prospective, open-label, multicenter study. Sixty patients with persistently high transaminases, positive HCV-RNA, CD4 count ≥300 cells/µl, and HIVRNA
ISSN:	0889-2229