Mandibular osteomyelitis developing due to a failed root canal treatment in a patient with multiple myeloma

Hundreds of patients with bisphosphonate-associated osteonecrosis have been reported worldwide, and in several of those individuals, evidence of osteomyelitis has been found. However, to our knowledge, osteomyelitis without osteonecrosis has not been reported in patients treated with bisphosphonates. This case report describes a patient with multiple myeloma in remission who was treated with bisphosphonates and osteomyelitis developed due to insufficient root canal treatment. The patient had bone marrow transplantation after the elimination of ongoing inflammation.