Synthesis and antimicrobial activity of some new 3-substituted benzyl-5-(4-chloro-2-piperidin-1yl- thiazole-5-yl-methylene)-thiazolidine-2,4-dione derivatives

Synthesis and antimicrobial activity of some new 3-substituted benzyl-5-(4-chloro-2-piperidin-1yl- thiazole-5-yl-methylene)-thiazolidine-2,4-dione derivatives

A new series of thiazolyl thiazolidine-2,4-dione (Va-f) were synthesized and their structures were elucidated by IR, $^1H$-NMR, mass spectra and elementary analysis. The synthesized compounds were tested for their antimicrobial activities against Candida albicans, Staphylococcus aureus, Bacillus sub...

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Veröffentlicht in:Turkish journal of chemistry 2006, Vol.30 (3), p.355-360
Hauptverfasser: ÜNLÜSOY, Meltem, Ceylan, ERTAN, Rahmiye, DÜNDAR, Oya, Bozdağ, ALTANLAR, Nurten
Format: Artikel
Sprache:eng
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Zusammenfassung:A new series of thiazolyl thiazolidine-2,4-dione (Va-f) were synthesized and their structures were elucidated by IR, $^1H$-NMR, mass spectra and elementary analysis. The synthesized compounds were tested for their antimicrobial activities against Candida albicans, Staphylococcus aureus, Bacillus subtilis and Escherichia coli. Compounds Va-b, Vd-f showed high activity against Escherichia coli comparable to ampicillin.
ISSN:1300-0527
1303-6130