Synthesis, spectral characterization and biological applications of tri-and diorganotin (IV) derivatives of 2-[N-(2,6-dichloro-3-methylphenyl) amino] benzoic acid

A series of tri- and diorganotin(IV) compounds with the general formulae $R_3SnL$ and $R_2SnL_2$ (where R = Me, n-Bu, Ph and L = 2-[N-(2,6-dichloro-3-methylphenyl)-amino]benzoate) were synthesized. These compounds were characterized by different instrumental methods such as infrared, multinuclear NM...

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Veröffentlicht in:Turkish journal of chemistry 2004, Vol.28 (1), p.17-26
Hauptverfasser: MAHARVI, Ghulam Mustafa, ALI, Sagib, KHAN, Khalid M, MAZHAR, Mohammad, BHATTI, Moazzam Hussain, SHAHID, Khadija, MAHMOOD, Sohail
Format: Artikel
Sprache:eng
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Zusammenfassung:A series of tri- and diorganotin(IV) compounds with the general formulae $R_3SnL$ and $R_2SnL_2$ (where R = Me, n-Bu, Ph and L = 2-[N-(2,6-dichloro-3-methylphenyl)-amino]benzoate) were synthesized. These compounds were characterized by different instrumental methods such as infrared, multinuclear NMR ($^1H$, $^{13}C$, $^{119}Sn$) and mass spectrometry. The spectroscopic investigation illustrates that the carboxylate group acts as a bidentate in solid state and as a monodentate in solution. Biological screening tests reveal that the investigated compounds have potential as antibacterial agents.
ISSN:1300-0527
1303-6130