Comparison of excretory urography, ultrasonography-guided percutaneous antegrade pyelography, and renal Doppler ultrasonography in rabbits with unilateral partial ureteral obstruction: an experimental study

The aim of this study was to compare diagnostic efficiency of excretory urography (EU), ultrasonography-guided percutaneous antegrade pyelography (UGPAP), and renal Doppler ultrasonography (DUS) in New Zealand rabbits (n= 20) experimentally induced unilateral partial ureteral obstruction. The resistive index (RI) value was obtained from all rabbits prior to the induction. A partial ureteral obstruction was created on the left ureter by laparotomy in all rabbits. Applications of direct renal DUS and renal DUS after furosemide administration were performed on days 1 and 10 post-operation. Rabbits were divided into two groups. Rabbits in the first group were subjected to EU, whereas those in the second group were subjected to UGPAP. The obstructive point was successfully determined all rabbits in the EU group on both days 1 and 10 post-operation, whereas in 8 rabbits on day 1 post-operation and all rabbits on day 10 post-operation in the UGPAP group. On both measurements, the mean RI values of the obstructed and non-obstructed kidneys were different (0.567 vs. 0.494; P 0.001). The RI value of non-obstructed kidneys decreased further with furosemide administration. The mean RI difference (RIΔ) after furosemide administration increased. In conclusion, in addition to EU and UGPAP, commonly used imagining methods in veterinary medicine, renal DUS after diuretic administration should be performed as a non-invasive technique to increase diagnostic efficiency of unilateral partial ureteral obstruction. Bu çalışmada, unilateral parsiyel üreteral obstruksiyon şekillendirilen Yeni Zellanda tavşanlarda (n= 20) ekskretör ürografi (EÜ), ultrason rehberli perkutan anterograd pyelografi (UGPAP) ve renal Doppler ultrasonografi (DUS) tanı yöntemlerinin karşılaştırılması amaçlanmıştır. Resistive indeks (RI) değeri, obstruksiyon şekillendirilmeden önce bütün tavşanlarda elde edildi ve laparatomi yapılarak tavşanların sol üreterlerinde parsiyel üreteral obstruksiyon oluşturuldu. Post-operatif 1. ve 10. günlerde bütün tavşanlara direkt renal DUS ve furosemid uygulaması sonrası DUS yapıldı. Tavşanlar onarlı iki gruba ayrıldı. Birinci gruba EÜ, ikinci gruba ise UGPAP yapıldı. İki farklı zamandaki EÜ grubunda bütün tavşanlarda; UGPAP grubunda ise 1. günde 8 tavşanda, 10. günde ise bütün tavşanlarda obstruktif odak belirlendi. Her iki ölçüm zamanında obstruktif böbreğin ortalama RI değeri (0.567) ile non-obstruktif böbreğin ortalama RI değerinde (0.494) arasında fark vardı (P 0.001).