Disposition of Work-Related Asthma in a Spanish Asthma Cohort : Comparison of Asthma Severity Between Employed and Retired Workers

Exposure to certain agents in the workplace can trigger occupational asthma or work-exacerbated asthma, both of which come under the heading of work-related asthma (WRA). Understanding the burden that WRA represents can help in the management of these patients. To assess the influence of occupation...

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Hauptverfasser: Romero Mesones, Christian, Cruz Carmona, María Jesús, Alobid, Isam, Barroso, Blanca, Arismendi, Ebymar, Barranco, Pilar, Betancor, Diana, Bobolea, Irina, Cárdaba, Blanca, Curto Sánchez, Elena, Domènech Casadevall, Gemma, Domínguez-Ortega, Javier, Espejo, David, González-Barcala, Francisco-Javier, Luna-Porta, Juan-Alberto, Martínez Rivera, Carlos, Méndez-Brea, Paula, Mullol, Joaquim, Olaguibel, Jose-Maria, Picado, Cesar, Plaza, Vicente, del Pozo, Victoria, Quirce, Santiago, Rial, Manuel-Jorge, Rodrigo-Muñoz, José María, Sastre, Joaquin, Serrano, Sandra, Soto-Retes, Lorena, Valero, Antonio, Valverde-Monge, Marcela, Muñoz Gall, Xavier, Universitat Autònoma de Barcelona
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Zusammenfassung:Exposure to certain agents in the workplace can trigger occupational asthma or work-exacerbated asthma, both of which come under the heading of work-related asthma (WRA). Understanding the burden that WRA represents can help in the management of these patients. To assess the influence of occupation on asthma in real life and analyze the characteristics of patients with WRA included in an asthma cohort. This was a prospective multicenter study of a cohort of consecutive patients with asthma. A standardized clinical history was completed. Patients were classified as having WRA or non-WRA. All patients underwent respiratory function tests, FeNO test, and methacholine challenge (methacholine concentration that causes a 20% drop in FEV) at the beginning of the study. They were classified into two groups, depending on their employment status: employed (group 1) or unemployed (group 2). Of the 480 patients included in the cohort, 82 (17%) received the diagnosis of WRA. Fifty-seven patients (70%) were still working. Mean age (SD) was 46 (10.69) years in group 1 and 57 (9.91) years in group 2 (P