Impact of late presentation of HIV infection on short-, mid- and long-term mortality and causes of death in a multicenter national cohort : 2004-2013

Impact of late presentation of HIV infection on short-, mid- and long-term mortality and causes of death in a multicenter national cohort : 2004-2013

To analyze the impact of late presentation (LP) on overall mortality and causes of death and describe LP trends and risk factors (2004-2013). Cox models and logistic regression were used to analyze data from a nation-wide cohort in Spain. LP is defined as being diagnosed when CD4 < 350 cells/ml o...

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Hauptverfasser: Bernardino, José Ignacio, Blanco, José Ramón, Del Amo, Julia, Garcia, Federico, Alejos, Belén, Monge, Susana, Jarrín, Inma, Muñoz-Fernández, M Ángeles, García-Merino, Isabel, de la Fuente, Jorge Gallego, Gadea, Carmen, Rodríguez, Juan Carlos, Luis Gómez, Juan, Remedios Alemán, María, García, Dácil, Pelazas, Ricardo, Labarga, Pablo, Rivas, Pablo, Blanco, Francisco, Vispo, Eugenia, Estrada, Vicente, Vergas García, Jorge, Bisbal, Otilia, Lagarde, Maria, Antonio Iribarren, José, José Aramburu, Maria, Rodríguez-Arrondo, Francisco, Aguado, Mirian, Gutiérrez, Félix, Masiá, Mar, Montolio, Fernando, Gregori Colomé, Joan, Adsuar, Araceli, Martinez, Maravillas, Muga, Roberto, Tor, Jordi, Berenguer, Juan, Gijón, Paloma, Tejerina, Francisco, Parras, Francisco Jose, Balsalobre, Pascual, Viladés, Consuelo, Veloso, Sergio, Vargas, Montserrat, Olona, Montserrat, Aguilar, Alba, Sirvent, Joan Josep, Alba, Verónica, Calavia, Olga, Montero, Marta, Calabuig, Eva, Salavert, Miguel, de la Serna, Ignacio Bernardino, Montes, María Luisa, Alcáriz, Natalia Stella, Mingorance, Jesús, de los Santos, Ignacio, Gómez, Ana, Oteo, José Antonio, Ibarra, Valvanera, Metola, Luis, Sanz, Mercedes, Pascual, Ascensión, Ramos, Carla, Arazo, Piedad, Dalmau, David, Jaén, Angels, Cairó, Mireia, Jordano, Queralt, Xercavins, Mariona, Font, Roser, Ibáñez, Laura, Rivero, María, Uriz, Javier, Arraiza, María Jesús, Sala, Montserrat, Nogueras, Mª Merce, Dronda, Fernando, Pérez Elías, Mª Jesus, Gutiérrez, Carolina, Martí, Paloma, Donat, Lucas, García, Federico, Parra, Jorge, Vinuesa, David, Fernández, Jose Angel, Puerta, Teresa, Carrió, Juan Carlos, Vera, Mar, Ballesteros, Juan, Mateo, Gracia, Riera, Melchor, Campins, Antoni A, Gil, Leire, Marinescu, Carmen, Palacios, Rosario, González, Carmen Maria, López-Cortés, Luis Fernando, Trastoy, Mónica, Espinosa, Nuria
Format: Artikel
Sprache:eng
Schlagworte:
Causes of death
Cohort study
Factors and trends
HIV
Late presentation
Mortality
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Zusammenfassung:To analyze the impact of late presentation (LP) on overall mortality and causes of death and describe LP trends and risk factors (2004-2013). Cox models and logistic regression were used to analyze data from a nation-wide cohort in Spain. LP is defined as being diagnosed when CD4 < 350 cells/ml or AIDS. Of 7165 new HIV diagnoses, 46.9% (CI:45.7-48.0) were LP, 240 patients died.First-year mortality was the highest (aHR = 10.3[CI:5.5-19.3]); between 1 and 4 years post-diagnosis, aHR = 1.9(1.2-3.0); and