Studies on the Asymmetric Dihydroxylation of Advanced Bryostatin C-Ring Segments

ABSTRACT The asymmetric dihydroxylation reaction of early stage and advanced Bryostatin C-ring precursors was evaluated. For homoallylic ethers and alcohols, several AD ligands were investigated including a novel class of quinidine-alkynes.

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Veröffentlicht in:Synthesis (Stuttgart) 2004-06, Vol.2004 (9), p.1391-1398
Hauptverfasser: Seidel, Martin C., Smits, René, Stark, Christian B., Frackenpohl, Jens, Gaertzen, Oliver, Hoffmann, H. Martin
Format: Artikel
Sprache:eng
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Zusammenfassung:ABSTRACT The asymmetric dihydroxylation reaction of early stage and advanced Bryostatin C-ring precursors was evaluated. For homoallylic ethers and alcohols, several AD ligands were investigated including a novel class of quinidine-alkynes.
ISSN:0039-7881
1437-210X
DOI:10.1055/s-2004-822400