Bi(OTf)3-[Bmim]PF6: A novel and Reusable Catalytic System for the Synthesis of cis-Aziridine Carboxylates
ABSTRACT Aldimines (generated in situ from aldehydes and amines) react readily with ethyl diazoacetate in the presence of 2 mol% of Bi(OTf) 3 or 5 mol% of Sc(OTf) 3 in [bmim]PF 6 ionic liquid to produce the corresponding aryl aziridine carboxylates in high yields with excellent CIS-diastereoselectiv...
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| Veröffentlicht in: | Synthesis (Stuttgart) 2003-07, Vol.2003 (9) |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | ABSTRACT
Aldimines (generated in situ from aldehydes and amines) react
readily with ethyl diazoacetate in the presence of 2 mol% of Bi(OTf)
3
or
5 mol% of Sc(OTf)
3
in [bmim]PF
6
ionic
liquid to produce the corresponding aryl aziridine carboxylates
in high yields with excellent CIS-diastereoselectivity.
The recovered ionic liquid containing catalyst was reused in three
to four subsequent runs with gradual decrease in activity. |
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| ISSN: | 0039-7881 1437-210X |
| DOI: | 10.1055/s-2003-40212 |