Identification of the novel HLA-DQA103:79 allele in a candidate bone marrow donor by next generation sequencing

Identification of the novel HLA-DQA103:79 allele in a candidate bone marrow donor by next generation sequencing

A single nucleotide mismatch within exon 3 of HLA-DQA1 differentiates the novel allele DQA1*03:79 from DQA1*03:15.

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Bibliographische Detailangaben
Veröffentlicht in:HLA 2024-09, Vol.104 (3), p.e15670
Hauptverfasser: Gaballa, Ahmed, Lundin, Nina, Eich, Torsten
Format: Artikel
Sprache:eng
Schlagworte:
Alleles
Base Sequence
Bone Marrow
Exons
High-Throughput Nucleotide Sequencing
Histocompatibility Testing - methods
HLA-DQ alpha-Chains - genetics
Humans
Medicin och hälsovetenskap
Polymorphism, Single Nucleotide
Tissue Donors
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Beschreibung
Zusammenfassung:A single nucleotide mismatch within exon 3 of HLA-DQA1 differentiates the novel allele DQA1*03:79 from DQA1*03:15.
ISSN:2059-2302
2059-2310
2059-2310
DOI:10.1111/tan.15670