Dermatologic adverse events caused by biologic treatments – Pathogenesis and management

Summary Biologics are approved for various dermatologic, allergic, rheumatic, and gastroenterologic inflammatory diseases, as well as for numerous malignancies. The dermatologic adverse events from treatment with biologics may resemble primary inflammatory diseases but differ in pathogenesis. In thi...

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Veröffentlicht in:Journal der Deutschen Dermatologischen Gesellschaft 2024-08, Vol.22 (8), p.1126-1136
Hauptverfasser: Trefzer, Laura Katharina, Pilz, Anna Caroline, Eyerich, Kilian
Format: Artikel
Sprache:eng
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Zusammenfassung:Summary Biologics are approved for various dermatologic, allergic, rheumatic, and gastroenterologic inflammatory diseases, as well as for numerous malignancies. The dermatologic adverse events from treatment with biologics may resemble primary inflammatory diseases but differ in pathogenesis. In this article, we describe five different pathogenic mechanisms of dermatologic adverse events. By studying these mechanisms, we hope to gain valuable insights into the pathogenesis of primary inflammatory diseases. In addition, in this article, we provide recommendations for the treatment and management of the dermatological adverse events induced by biologics.
ISSN:1610-0379
1610-0387
1610-0387
DOI:10.1111/ddg.15360