Inflammatory profile of lower risk myelodysplastic syndromes

Summary The precise link between inflammation and pathogenesis of myelodysplastic syndrome (MDS) is yet to be fully established. We developed a novel method to measure ASC/NLRP3 protein specks which are specific for the NLRP3 inflammasome only. We combined this with cytokine profiling to characteris...

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Veröffentlicht in:	British journal of haematology 2024-09, Vol.205 (3), p.1044-1054
Hauptverfasser:	Topping, Joanne, Taylor, Adele, Nadat, Fatima, Crouch, Simon, Ibbotson, Alice, Čermák, Jaroslav, Symeonidis, Argiris, Tatic, Aurelia, Langemeijer, Saskia, Hellström‐Lindberg, Eva, Culligan, Dominic, Garelius, Hege Gravdahl, Ashcroft, John, Nga, Emma, Parker, Jane, Kolade, Seye, McDermott, Michael F., De Witte, Theo, Bowen, David, Smith, Alexandra, Cargo, Catherine, Savic, Sinisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers - blood Blood transfusion Case-Control Studies Cytokines Cytokines - blood Erythrocytes Female Humans Inflammasomes inflammation Inflammation - blood Inflammatory diseases Interferon Male MDS Middle Aged Myelodysplastic syndrome Myelodysplastic Syndromes - blood NLR Family, Pyrin Domain-Containing 3 Protein - blood NLRP3 inflammasome Pathogenesis Tumor necrosis factor Tumor necrosis factor-TNF
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