Spider Silk Protein Forms Amyloid‐Like Nanofibrils through a Non‐Nucleation‐Dependent Polymerization Mechanism (Small 46/2023)

Spider Silk ProteinsBoth spider silk protein and Alzheimer's disease associated amyloid‐β peptide can assemble into silk‐like fibers that consist of nanofibrils. Spider silk proteins' unique primary structures have evolved to allow functional amyloid‐like properties and direct their fibrillization pathways to avoid formation of cytotoxic intermediates. More details can be found in article number 2304031 by Gefei Chen and co‐workers.