Risk factors for mortality in infancy and childhood in children with major congenital anomalies: A European population‐based cohort study

Background Preterm birth and young maternal age are known risk factors for infant and childhood mortality. There is limited knowledge of the impact of these risk factors in children born with major congenital anomalies (CAs), who have inherently higher risks of death compared with other children. Objectives To investigate the risk factors for mortality up to age 10 years in children born with specific major CAs. Methods This population‐based cohort study involved 150,198 livebirths from 1995 to 2014 in 13 European CA registries linked to mortality data. Cox proportional hazards models estimated the association of gestational age, maternal age and child's sex with death