Imaging endogenous dopamine occupancy of the D2 receptor in rat brain with [11C]MNPA
Conclusions: Assuming that there was no upregulation in the density of the D2 receptor during the short period of DA depletion, these results suggest that a significant proportion of striatal D2 receptors in the high affinity state is occupied by endogenous dopamine under baseline conditions.
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| Veröffentlicht in: | NEUROIMAGE 2006, Vol.31, p.T119-T119 |
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| container_title | NEUROIMAGE |
| container_volume | 31 |
| creator | Seneca, Nicholas Liow, J.S. Zoghbi, S. Musachio, J.L. Hong, J. Pike, V.W. Halldin, C. Innis, R.B. |
| description | Conclusions: Assuming that there was no upregulation in the density of the D2 receptor during the short period of DA depletion, these results suggest that a significant proportion of striatal D2 receptors in the high affinity state is occupied by endogenous dopamine under baseline conditions. |
| doi_str_mv | 10.1016/j.neuroimage.2006.04.105 |
| format | Article |
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| language | eng |
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| source | Access via ScienceDirect (Elsevier); ProQuest Central UK/Ireland |
| subjects | Dopamine Medicin och hälsovetenskap Parkinson's disease Rodents |
| title | Imaging endogenous dopamine occupancy of the D2 receptor in rat brain with [11C]MNPA |
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