Synthesis of the marine alkaloid caulersin

A three-step synthesis of caulersin ( 3 ) from indole-2-acetic acid methyl ester and indole-2-carbonyl chloride is described. As the spectral data of the synthetic sample differed from those reported for the natural product, the structure was determined by X-ray crystallography. Graphic

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Veröffentlicht in:Tetrahedron 2004, Vol.60 (9), p.2147-2153
Hauptverfasser: Wahlström, Niklas, Stensland, Birgitta, Bergman, Jan
Format: Artikel
Sprache:eng
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Zusammenfassung:A three-step synthesis of caulersin ( 3 ) from indole-2-acetic acid methyl ester and indole-2-carbonyl chloride is described. As the spectral data of the synthetic sample differed from those reported for the natural product, the structure was determined by X-ray crystallography. Graphic
ISSN:0040-4020
1464-5416
1464-5416
DOI:10.1016/j.tet.2003.12.046