Cyanoacetylation of Indoles, Pyrroles and Aromatic Amines with the Combination Cyanoacetic Acid and Acetic Anhydride

ABSTRACT Cyanoacetic acid was activated with acetic anhydride and when heated this reagent reacted with a variety of both activated and deactivated pyrroles, indoles and aniline derivatives.

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Bibliographische Detailangaben
Veröffentlicht in:	Synthesis (Stuttgart) 2004, Vol.2004 (16), p.2760-2765
Hauptverfasser:	Slätt, Johnny, Romero, Ivan, Bergman, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	acylation arom electrophilic substitution indole pyrrole carbazole propanenitrile oxo cyanoacetylation acetic anhydride cyanoacetic acid cyanoacetamide cyanophenyl cyanoacetylation acetic anhydride cyanoacetic acid cyanoacetylation indole pyrrole arom amine cyanoacetic acid acetic anhydride indole propanenitrile oxo cyanoacetylation acetic anhydride cyanoacetic acid Medicin och hälsovetenskap practical synthetic procedures pyrimidine propanenitrile oxo cyanoacetylation acetic anhydride cyanoacetic acid pyrrole propanenitrile oxo cyanoacetylation acetic anhydride cyanoacetic acid
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Beschreibung
Zusammenfassung:	ABSTRACT Cyanoacetic acid was activated with acetic anhydride and when heated this reagent reacted with a variety of both activated and deactivated pyrroles, indoles and aniline derivatives.
ISSN:	0039-7881 1437-210X 1437-210X
DOI:	10.1055/s-2004-831164