Familial testicular cancer: lack of evidence for trinucleotide repeat expansions and association with PKD1 in one family

[...]these findings are interesting and have not been described before. Besides chance coincidence, a common aetiology for both conditions cannot be ruled out, especially in view of the fact that the kidney and testis share the same embryological origin, the urogenital ridge. [...]we failed to find...

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Veröffentlicht in:Journal of medical genetics 1999-04, Vol.36 (4), p.348-349
Hauptverfasser: TEH, B T, LINBLAD, K, NORD, B, KYTÖLÄ, S, SCHALLING, M, LARSSON, C, RAPLEY, E, BIGGS, P, HUDDART, R, STRATTON, M, HII, S, NICOL, D
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Sprache:eng
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Zusammenfassung:[...]these findings are interesting and have not been described before. Besides chance coincidence, a common aetiology for both conditions cannot be ruled out, especially in view of the fact that the kidney and testis share the same embryological origin, the urogenital ridge. [...]we failed to find any evidence of excess CAG/CTG expansions in our series as compared with the general white population.
ISSN:0022-2593
1468-6244
DOI:10.1136/jmg.36.4.348