Progressive cutaneous sarcoidosis responding to anti-tumor necrosis factor-α therapy

Progressive cutaneous sarcoidosis responding to anti-tumor necrosis factor-α therapy

We describe a patient with widespread and progressive cutaneous sarcoidosis who was successfully treated with anti-tumor necrosis factor-α monoclonal antibody, infliximab, suggesting that inhibition of tumor necrosis factor-α may be useful as targeted treatment in cutaneous sarcoidosis. (J Am Acad D...

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Veröffentlicht in:Journal of the American Academy of Dermatology 2003-02, Vol.48 (2), p.290-293
Hauptverfasser: Mallbris, Lotus, Ljungberg, Anders, Hedblad, Mari-Anne, Larsson, Per, Ståhle-Bäckdahl, Mona
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Antibodies, Monoclonal - therapeutic use
Biological and medical sciences
Dermatologic Agents - therapeutic use
Disease Progression
Genotype
Humans
Infliximab
Male
Medical sciences
Sarcoidosis - drug therapy
Sarcoidosis - genetics
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Skin Diseases - drug therapy
Tumor Necrosis Factor-alpha
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Zusammenfassung:We describe a patient with widespread and progressive cutaneous sarcoidosis who was successfully treated with anti-tumor necrosis factor-α monoclonal antibody, infliximab, suggesting that inhibition of tumor necrosis factor-α may be useful as targeted treatment in cutaneous sarcoidosis. (J Am Acad Dermatol 2003;48:290-3.)
ISSN:0190-9622
1097-6787
DOI:10.1067/mjd.2003.228