Serum lipids and hippocampal volume: The link to Alzheimer's disease?
The association between hippocampal volume (as a presumed index of Alzheimer's disease pathology) with serum total cholesterol, high‐density lipoprotein cholesterol, and low‐density lipoprotein cholesterol was studied in 86 elderly subjects with a range of cognitive functions. High‐density lipo...
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| Veröffentlicht in: | Annals of neurology 2004-11, Vol.56 (5), p.745-749 |
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| container_end_page | 749 |
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| container_issue | 5 |
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| container_title | Annals of neurology |
| container_volume | 56 |
| creator | Wolf, Henrike Hensel, Anke Arendt, Thomas Kivipelto, Miia Winblad, Bengt Gertz, Hermann-Josef |
| description | The association between hippocampal volume (as a presumed index of Alzheimer's disease pathology) with serum total cholesterol, high‐density lipoprotein cholesterol, and low‐density lipoprotein cholesterol was studied in 86 elderly subjects with a range of cognitive functions. High‐density lipoprotein cholesterol, but not low‐density lipoprotein cholesterol or total cholesterol, was associated with hippocampal volume and dementia. This is compatible with protective effects of high‐density lipoprotein cholesterol on hippocampal atrophy and Alzheimer's disease. Ann Neurol 2004;56:745–749 |
| doi_str_mv | 10.1002/ana.20289 |
| format | Article |
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High‐density lipoprotein cholesterol, but not low‐density lipoprotein cholesterol or total cholesterol, was associated with hippocampal volume and dementia. This is compatible with protective effects of high‐density lipoprotein cholesterol on hippocampal atrophy and Alzheimer's disease. Ann Neurol 2004;56:745–749</description><identifier>ISSN: 0364-5134</identifier><identifier>EISSN: 1531-8249</identifier><identifier>DOI: 10.1002/ana.20289</identifier><identifier>PMID: 15505826</identifier><identifier>CODEN: ANNED3</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Aged ; Aged, 80 and over ; Alzheimer Disease - blood ; Alzheimer Disease - pathology ; Analysis of Variance ; Biological and medical sciences ; Cholesterol, HDL - blood ; Cholesterol, LDL - blood ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; Female ; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy ; Hippocampus - pathology ; Humans ; Lipids - blood ; Male ; Medical sciences ; Medicin och hälsovetenskap ; Nervous system (semeiology, syndromes) ; Neurology</subject><ispartof>Annals of neurology, 2004-11, Vol.56 (5), p.745-749</ispartof><rights>Copyright © 2004 American Neurological Association</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5729-52bb507af6ee1fce75dd85e5fefad560e5b09ab1f1c4cd01e08a65e80eafbab53</citedby><cites>FETCH-LOGICAL-c5729-52bb507af6ee1fce75dd85e5fefad560e5b09ab1f1c4cd01e08a65e80eafbab53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fana.20289$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fana.20289$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,780,784,885,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16281694$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15505826$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:1954114$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Wolf, Henrike</creatorcontrib><creatorcontrib>Hensel, Anke</creatorcontrib><creatorcontrib>Arendt, Thomas</creatorcontrib><creatorcontrib>Kivipelto, Miia</creatorcontrib><creatorcontrib>Winblad, Bengt</creatorcontrib><creatorcontrib>Gertz, Hermann-Josef</creatorcontrib><title>Serum lipids and hippocampal volume: The link to Alzheimer's disease?</title><title>Annals of neurology</title><addtitle>Ann Neurol</addtitle><description>The association between hippocampal volume (as a presumed index of Alzheimer's disease pathology) with serum total cholesterol, high‐density lipoprotein cholesterol, and low‐density lipoprotein cholesterol was studied in 86 elderly subjects with a range of cognitive functions. 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Cerebral palsy</subject><subject>Hippocampus - pathology</subject><subject>Humans</subject><subject>Lipids - blood</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicin och hälsovetenskap</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><issn>0364-5134</issn><issn>1531-8249</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9v1DAQxS0EapfSA18A5QKIQ1pPknGSXtCq7Rakqj20FRIXa5JMtGbzD3tDKZ8eL5t2TxWnsUa_NzPPT4i3II9AyuiYOjqKZJTlL8QMMIYwi5L8pZjJWCUhQpzsi9fO_ZBS5grkntgHRIlZpGbi_Ibt2AaNGUzlAuqqYGmGoS-pHagJfvXN2PJJcLtkj3SrYN0H8-bPkk3L9qMLKuOYHH9-I17V1Dg-nOqBuFuc355-CS-vL76ezi_DEtMoDzEqCpQp1YoZ6pJTrKoMGWuuqUIlGQuZUwE1lElZSWCZkULOJFNdUIHxgQi3c909D2OhB2tasg-6J6On1sq_WGMWJ2rDp8_yg-2rnehRCDkmAIlXftgqPfZzZLfWrXElNw113I9Oq1RGMWD-XxC88cS79-CnLVja3jnL9dM1IPUmRu1j1P9i9Oy7aehYtFztyCk3D7yfAHIlNbWlrjRux6koA5VvbBxvuXvT8MPzG_X8av64evpi49b8-0lBduU9xynqb1cX-mbxPTmDfKHP4r8pQcRf</recordid><startdate>200411</startdate><enddate>200411</enddate><creator>Wolf, Henrike</creator><creator>Hensel, Anke</creator><creator>Arendt, Thomas</creator><creator>Kivipelto, Miia</creator><creator>Winblad, Bengt</creator><creator>Gertz, Hermann-Josef</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Willey-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope></search><sort><creationdate>200411</creationdate><title>Serum lipids and hippocampal volume: The link to Alzheimer's disease?</title><author>Wolf, Henrike ; Hensel, Anke ; Arendt, Thomas ; Kivipelto, Miia ; Winblad, Bengt ; Gertz, Hermann-Josef</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5729-52bb507af6ee1fce75dd85e5fefad560e5b09ab1f1c4cd01e08a65e80eafbab53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Alzheimer Disease - blood</topic><topic>Alzheimer Disease - pathology</topic><topic>Analysis of Variance</topic><topic>Biological and medical sciences</topic><topic>Cholesterol, HDL - blood</topic><topic>Cholesterol, LDL - blood</topic><topic>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</topic><topic>Female</topic><topic>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. 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| ispartof | Annals of neurology, 2004-11, Vol.56 (5), p.745-749 |
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| language | eng |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | Aged Aged, 80 and over Alzheimer Disease - blood Alzheimer Disease - pathology Analysis of Variance Biological and medical sciences Cholesterol, HDL - blood Cholesterol, LDL - blood Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Hippocampus - pathology Humans Lipids - blood Male Medical sciences Medicin och hälsovetenskap Nervous system (semeiology, syndromes) Neurology |
| title | Serum lipids and hippocampal volume: The link to Alzheimer's disease? |
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