Long-term follow-up of lung and heart transplant recipients with pre-transplant malignancies

Background Concern regarding recurrence of pre-transplant (Tx) malignancy has disqualified patients from Tx. Because this has been poorly studied in lung and heart Tx recipients our aim was to investigate the influence of pre-Tx malignancy on post-Tx recurrence and long-term survival, focusing on pr...

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Veröffentlicht in:	The Journal of heart and lung transplantation 2012-12, Vol.31 (12), p.1276-1280
Hauptverfasser:	Sigurdardottir, Vilborg, MD, PhD, FEBTM, Bjortuft, Oystein, MD, PhD, Eiskjær, Hans, MD, PhD, Ekmehag, Bjorn, MD, PhD, Gude, Einar, MD, Gustafsson, Finn, MD, PhD, Hagerman, Inger, MD, PhD, Halme, Maija, MD, PhD, Lommi, Jyri, MD, PhD, Mared, Lena, MD, Riise, Gerdt C, MD, PhD, Simonsen, Svein, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cardiac and Cardiovascular Systems Cardiology. Vascular system Clinical Medicine Disease-Free Survival Female Follow-Up Studies Heart Transplantation Humans Kardiologi Klinisk medicin Lung Transplantation Male Medical and Health Sciences Medical sciences Medicin och hälsovetenskap Neoplasms - complications Postoperative Complications pre-transplant malignancy Recurrence Retrospective Studies Risk Factors Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart survival Time Factors
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Zusammenfassung:	Background Concern regarding recurrence of pre-transplant (Tx) malignancy has disqualified patients from Tx. Because this has been poorly studied in lung and heart Tx recipients our aim was to investigate the influence of pre-Tx malignancy on post-Tx recurrence and long-term survival, focusing on pre-operative cancer-free intervals. Methods From our lung and heart Tx programs (1983 to 2011) we retrospectively identified 111 (lung, 37; heart, 74) of 3,830 recipients with 113 pre-Tx malignancies. The patients were divided into 3 groups by pre-Tx cancer-free interval: Group I,
ISSN:	1053-2498 1557-3117 1557-3117
DOI:	10.1016/j.healun.2012.09.007