The Years of the Monkey

The fact that mammals are diploid sets a barrier to rapidly understand the function of non-coding and coding genes in the genome. Recently, Yang et al reported successful derivation of monkey haploid embryonic stem cells from parthenotes, which provide an effective platform for studying mammalian ge...

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Veröffentlicht in:Cell research 2013-10, Vol.23 (10), p.1161-1162
Hauptverfasser: Lian, Xiaojun, Chien, Kenneth R
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Chien, Kenneth R
description The fact that mammals are diploid sets a barrier to rapidly understand the function of non-coding and coding genes in the genome. Recently, Yang et al reported successful derivation of monkey haploid embryonic stem cells from parthenotes, which provide an effective platform for studying mammalian gene function and enable reverse genetic screening of genes for recessive phenotypes in monkeys.
doi_str_mv 10.1038/cr.2013.111
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subjects 631/136/532/2117
692/308/2056
Animals
Biomedical and Life Sciences
Cell Biology
Embryonic Stem Cells - cytology
Genetic screening
Haploidy
Life Sciences
Macaca fascicularis - embryology
Mammals
Medicin och hälsovetenskap
Research Highlight
Stem cells
单性生殖
反向遗传
哺乳动物
基因功能
基因组
猴子
编码基因
胚胎干细胞
title The Years of the Monkey
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