The Years of the Monkey

The fact that mammals are diploid sets a barrier to rapidly understand the function of non-coding and coding genes in the genome. Recently, Yang et al reported successful derivation of monkey haploid embryonic stem cells from parthenotes, which provide an effective platform for studying mammalian ge...

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Veröffentlicht in:	Cell research 2013-10, Vol.23 (10), p.1161-1162
Hauptverfasser:	Lian, Xiaojun, Chien, Kenneth R
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136/532/2117 692/308/2056 Animals Biomedical and Life Sciences Cell Biology Embryonic Stem Cells - cytology Genetic screening Haploidy Life Sciences Macaca fascicularis - embryology Mammals Medicin och hälsovetenskap Research Highlight Stem cells 单性生殖反向遗传哺乳动物基因功能基因组猴子编码基因胚胎干细胞
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Beschreibung
Zusammenfassung:	The fact that mammals are diploid sets a barrier to rapidly understand the function of non-coding and coding genes in the genome. Recently, Yang et al reported successful derivation of monkey haploid embryonic stem cells from parthenotes, which provide an effective platform for studying mammalian gene function and enable reverse genetic screening of genes for recessive phenotypes in monkeys.
ISSN:	1001-0602 1748-7838 1748-7838
DOI:	10.1038/cr.2013.111