Neuropsychiatric symptoms in dementia—A role for neuroinflammation?

Highlights • Cerebrospinal fluid cytokines were measured using ELISA. • IL-10 appeared to play a beneficial role with regard to NPSD. • Immunologically based interventions for specific NPSD may be beneficial.

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Bibliographische Detailangaben
Veröffentlicht in:	Brain research bulletin 2014-09, Vol.108, p.88-93
Hauptverfasser:	Holmgren, Simon, Hjorth, Erik, Schultzberg, Marianne, Lärksäter, Marie, Frenkel, Dan, Tysen-Bäckström, Ann Christine, Aarsland, Dag, Freund-Levi, Yvonne
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer's disease Behavioural symptoms BPSD Cerebrospinal fluid Cytokines Cytokines - cerebrospinal fluid Dementia - cerebrospinal fluid Dementia - complications Encephalitis - cerebrospinal fluid Encephalitis - complications Female Humans Interleukin-10 - cerebrospinal fluid Interleukin-6 - cerebrospinal fluid Male Neurology Neuropsychological Tests NPSD Tumor Necrosis Factor-alpha - cerebrospinal fluid
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Beschreibung
Zusammenfassung:	Highlights • Cerebrospinal fluid cytokines were measured using ELISA. • IL-10 appeared to play a beneficial role with regard to NPSD. • Immunologically based interventions for specific NPSD may be beneficial.
ISSN:	0361-9230 1873-2747 1873-2747
DOI:	10.1016/j.brainresbull.2014.09.003