Eye and hand motor interactions with the Symbol Digit Modalities Test in early multiple sclerosis

Eye and hand motor interactions with the Symbol Digit Modalities Test in early multiple sclerosis

Abstract Purpose Eye and hand motor dysfunction may be present early in the disease course of relapsing-remitting multiple sclerosis (RRMS), and can affect the results on visual and written cognitive tests. We aimed to test for differences in saccadic initiation time (SI time) between RRMS patients...

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Veröffentlicht in:Multiple sclerosis and related disorders 2015-11, Vol.4 (6), p.585-589
Hauptverfasser: Nygaard, Gro O, de Rodez Benavent, Sigrid A, Harbo, Hanne F, Laeng, Bruno, Sowa, Piotr, Damangir, Soheil, Bernhard Nilsen, Kristian, Etholm, Lars, Tønnesen, Siren, Kerty, Emilia, Drolsum, Liv, Inge Landrø, Nils, Celius, Elisabeth G
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Cognition
Disability Evaluation
Evoked Potentials, Visual
Eye
Female
Hand - physiopathology
Hand function
Humans
Linear Models
Male
Motor Skills - physiology
Multiple sclerosis
Multiple sclerosis functional composite
Multiple Sclerosis, Relapsing-Remitting - diagnosis
Multiple Sclerosis, Relapsing-Remitting - physiopathology
Multiple Sclerosis, Relapsing-Remitting - psychology
Multivariate Analysis
Neurologic Examination
Neurology
Neuropsychological Tests
Saccades
Saccades - physiology
Severity of Illness Index
Symbol Digit Modalities Test
Symptom assessment
Time Factors
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Beschreibung
Zusammenfassung:Abstract Purpose Eye and hand motor dysfunction may be present early in the disease course of relapsing-remitting multiple sclerosis (RRMS), and can affect the results on visual and written cognitive tests. We aimed to test for differences in saccadic initiation time (SI time) between RRMS patients and healthy controls, and whether SI time and hand motor speed interacted with the written version of the Symbol Digit Modalities Test (wSDMT). Methods Patients with RRMS ( N =44, age 35.1±7.3 years), time since diagnosis
ISSN:2211-0348
2211-0356
DOI:10.1016/j.msard.2015.08.003