Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding

Aims/hypothesis Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a c...

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Veröffentlicht in:	Diabetologia 2016-04, Vol.59 (4), p.799-812
Hauptverfasser:	Gillberg, Linn, Perfilyev, Alexander, Brøns, Charlotte, Thomasen, Martin, Grunnet, Louise G., Volkov, Petr, Rosqvist, Fredrik, Iggman, David, Dahlman, Ingrid, Risérus, Ulf, Rönn, Tina, Nilsson, Emma, Vaag, Allan, Ling, Charlotte
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Vesicular Transport - genetics Adipose Tissue - metabolism Adult Birth weight Body fat Clinical Medicine Diabetes Diabetes Mellitus, Type 2 - genetics Diet Diet, High-Fat - adverse effects DNA methylation DNA Methylation - genetics Endocrinology and Diabetes Endokrinologi och diabetes Epigenetics Epigenomics Fatty Acid Desaturases - genetics Gene expression Genomes Health care High-fat overfeeding Human Physiology Humans Infant, Low Birth Weight - physiology Insulin resistance Internal Medicine Klinisk medicin Low birthweight Male Medical and Health Sciences Medicin och hälsovetenskap Medicine Medicine & Public Health Metabolic Diseases Metabolic disorders Metabolism Musculoskeletal system Nerve Tissue Proteins - genetics Nutrition research Obesity Transcriptome - genetics Type 2 diabetes Young Adult
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