Diabetes mellitus, metformin and head and neck cancer

Highlights • There was an inverse association between diabetes and head and neck cancer. • The inverse association may be explained by metformin, since in separated analysis by use of metformin in diabetic patients there was protection for head and neck cancer only among metformin users.

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Bibliographische Detailangaben
Veröffentlicht in:	Oral oncology 2016-10, Vol.61, p.47-54
Hauptverfasser:	Figueiredo, Rejane Augusta de Oliveira, Weiderpass, Elisabete, Tajara, Eloiza Helena, Ström, Peter, Carvalho, André Lopes, de Carvalho, Marcos Brasilino, Kanda, Jossi Ledo, Moyses, Raquel Ajub, Wünsch-Filho, Victor
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Case-control studies Diabetes mellitus Diabetes Mellitus - drug therapy Female Head and neck cancer Head and Neck Neoplasms - complications Hematology, Oncology and Palliative Medicine Humans Hypoglycemic Agents - therapeutic use Male Metformin Metformin - therapeutic use Middle Aged Otolaryngology
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Beschreibung
Zusammenfassung:	Highlights • There was an inverse association between diabetes and head and neck cancer. • The inverse association may be explained by metformin, since in separated analysis by use of metformin in diabetic patients there was protection for head and neck cancer only among metformin users.
ISSN:	1368-8375 1879-0593
DOI:	10.1016/j.oraloncology.2016.08.006