Outbreak of enterovirus D68 of the new B3 lineage in Stockholm, Sweden, August to September 2016

We report an enterovirus D68 (EV-D68) outbreak in Stockholm Sweden in 2016. Between 22 August and 25 September EV-D68 was detected in 74/495 respiratory samples analysed at the Karolinska University Hospital. During the peak week, 30/91 (33%) samples were EV-D68 positive. Viral protein (VP)P4/VP2 se...

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Veröffentlicht in:	Euro surveillance : bulletin européen sur les maladies transmissibles 2016-11, Vol.21 (46), p.1
Hauptverfasser:	Dyrdak, Robert, Grabbe, Malin, Hammas, Berit, Ekwall, Jonas, Hansson, Karin E, Luthander, Joachim, Naucler, Pontus, Reinius, Henrik, Rotzén-Östlund, Maria, Albert, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Child Child, Preschool Disease Outbreaks Enterovirus - classification Enterovirus - isolation & purification Enterovirus D, Human - classification Enterovirus D, Human - genetics Enterovirus D, Human - isolation & purification Enterovirus Infections - epidemiology Enterovirus Infections - virology Epidemics Fatalities Female Genetic Variation Hospitals Humans Infant Male Phylogeny Rapid Communication Respiratory diseases Respiratory Tract Infections - epidemiology Reverse Transcriptase Polymerase Chain Reaction Sequence Analysis, DNA Studies Sweden - epidemiology Viral Structural Proteins - genetics Viruses
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Zusammenfassung:	We report an enterovirus D68 (EV-D68) outbreak in Stockholm Sweden in 2016. Between 22 August and 25 September EV-D68 was detected in 74/495 respiratory samples analysed at the Karolinska University Hospital. During the peak week, 30/91 (33%) samples were EV-D68 positive. Viral protein (VP)P4/VP2 sequencing revealed that cases were caused by B3 lineage strains. Forty-four (59%) EV-D68-positive patients were children aged ≤ 5 years. Ten patients had severe respiratory or neurological symptoms and one died.
ISSN:	1560-7917 1025-496X 1560-7917
DOI:	10.2807/1560-7917.ES.2016.21.46.30403