Incidence and prognostic significance of isolated trisomies in adult acute myeloid leukemia: A population‐based study from the Swedish AML registry

Objectives and Methods To ascertain the incidence/clinical implications of isolated autosomal trisomies in adult acute myeloid leukemia (AML), all such cases were retrieved from the Swedish AML Registry. Results Of the 3179 cytogenetically informative AMLs diagnosed January 1997‐May 2015, 246 (7.7%)...

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Veröffentlicht in:European journal of haematology 2017-05, Vol.98 (5), p.493-500
Hauptverfasser: Lazarevic, Vladimir Lj, Rosso, Aldana, Juliusson, Gunnar, Antunovic, Petar, Derolf, Åsa Rangert, Deneberg, Stefan, Möllgård, Lars, Uggla, Bertil, Wennström, Lovisa, Wahlin, Anders, Höglund, Martin, Lehmann, Sören, Johansson, Bertil
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Sprache:eng
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Zusammenfassung:Objectives and Methods To ascertain the incidence/clinical implications of isolated autosomal trisomies in adult acute myeloid leukemia (AML), all such cases were retrieved from the Swedish AML Registry. Results Of the 3179 cytogenetically informative AMLs diagnosed January 1997‐May 2015, 246 (7.7%) had isolated trisomies. The frequency increased by age (2.4% at age 18‐60 years vs. 23% at >60 years; P
ISSN:0902-4441
1600-0609
1600-0609
DOI:10.1111/ejh.12861